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Fructose Fogs the Brain New Study on Rats Suggests

  • Posted on May 16, 2012 at 12:10 pm

A high intake of fructose impairs the cognitive abilities of rats by interfering with insulin signaling, but omega-3 fatty acids (n-3) reduces those negative effects effects according to a study from the Department of Integrative Biology and Physiology UCLA published in Journal of Physiology.

Although headlines today, including my own, emphasize the study’s findings regarding the impairing effects of high levels of fructose, the study also highlights the importance of n-3 acids, specifically DHA, to cognitive function. The authors of the study conclude: “In terms of public health, these results support the encouraging possibility that healthy diets can attenuate the action of unhealthy diets such that the right combination of foods is crucial for a healthy brain.”

The study, conducted by Rahul Agrawal1 and Fernando Gomez-Pinilla, consisted of four groups of six rats:

  • one group ate an n-3 deficient diet with a fructose solution
  • one group ate an n-3 deficient diet without a fructose solution
  • one group ate an n-3 sufficient diet with a fructose solution
  • one group ate an n-3 sufficient diet without a fructose solution

Each group was tested on a Barnes maze, a standard measure of spatial learning and memory in rodents. Prior to beginning their special diets all of the rats had been trained in the maze for a five days were found to be of equal cognitive condition.

The study found that an n-3 deficient diet hampered the rats’ performance on the maze, and that adding high fructose intake to an n-3 deficient diet made things substantially worse. The rats with an n-3 sufficient diet but a high level of fructose did significantly better than those with a n-3 deficient diet and a high level of fructose, but still did worse than those with a deficient n-3 level but no fructose. Here’s an illustration of the latency in completing the maze (lower is better):

Comparison of latency times in Barnes maze test

The study notes: “Although there was a preference towards fructose drinking in comparison to the food intake, no differences were observed in body weight and total caloric intake, thus suggesting that obesity is not a major contributor to altered memory functions in this model.”

Full Paper: The Journal of Physiology: ‘Metabolic syndrome’ in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition

This is a new study and has yet to be replicated, and so far its implications for human diets is unclear. “We’re not talking about naturally occurring fructose in fruits, which also contain important antioxidants,” Gomez-Pinilla said in a pres release. “We’re concerned about high-fructose corn syrup that is added to manufactured food products as a sweetener and preservative.”

Although studies have found positive benefits in taking DHA supplements (see Wikipedia for an overview), previous study by Nutritional Sciences Division at King’s College London on the DHA levels in vegans and vegetarians concluded that although those who don’t eat meat have significantly lower levels of DHA “There is no evidence of adverse effects on health or cognitive function with lower DHA intake in vegetarians.” However, there are now a number of algae based vegan DHA supplements.

From http://technoccult.net/archives/2012/05/16/fructose-fogs-the-brain-new-study-on-rats-suggests/

History of the N-Back Training Exercise

  • Posted on April 24, 2012 at 5:19 pm

Dan Hurley wrote a lengthy New York Times piece covering the origins of the n-back training exercise, which purportedly improves fluid intelligence in those who practice it daily:

The study, by a Swedish neuroscientist named Torkel Klingberg, involved just 14 children, all with A.D.H.D. Half participated in computerized tasks designed to strengthen their working memory, while the other half played less challenging computer games. After just five weeks, Klingberg found that those who played the working-memory games fidgeted less and moved about less. More remarkable, they also scored higher on one of the single best measures of fluid intelligence, the Raven’s Progressive Matrices. Improvement in working memory, in other words, transferred to improvement on a task the children weren’t training for. [...]

When Klingberg’s study came out, both Jaeggi and Buschkuehl were doctoral candidates in cognitive psychology at the University of Bern, Switzerland. Since his high-school days as a Swiss national-champion rower, Buschkuehl had been interested in the degree to which skills — physical and mental — could be trained. Intrigued by Klingberg’s suggestion that training working memory could improve fluid intelligence, he showed the paper to Jaeggi, who was studying working memory with a test known as the N-back. “At that time there was pretty much no evidence whatsoever that you can train on one particular task and get transfer to another task that was totally different,” Jaeggi says. That is, while most skills improve with practice, the improvement is generally domain-specific: you don’t get better at Sudoku by doing crosswords. And fluid intelligence was not just another skill; it was the ultimate cognitive ability underlying all mental skills, and supposedly immune from the usual benefits of practice. To find that training on a working-memory task could result in an increase in fluid intelligence would be cognitive psychology’s equivalent of discovering particles traveling faster than light.

New York Times: Can You Make Yourself Smarter?

Hurley mentions one unpublished study that has failed to replicate the n-back results, but otherwise it is still holding up in tests. However, you should always be weary of the decline effect.

But really, the biggest drawback is probably that it’s hard to get people to start or stick with the n-back. I’ve known about for years now and still haven’t done it.

From http://technoccult.net/archives/2012/04/24/history-of-the-n-back-training-exercise/

The Atlantic: Stratfor Was Always a Joke

  • Posted on February 27, 2012 at 7:50 pm

It’s clear now that, much like HBGary before it (see: Inside the World of Wannabe Cyberspooks for Hire) private security research firm Stratfor is a joke.

But according to The Atlantic International Editor Max Fisher, Stratfor was always a joke in the foreign policy community:

The group’s reputation among foreign policy writers, analysts, and practitioners is poor; they are considered a punchline more often than a source of valuable information or insight. As a former recipient of their “INTEL REPORTS” (I assume someone at Stratfor signed me up for a trial subscription, which appeared in my inbox unsolicited), what I found was typically some combination of publicly available information and bland “analysis” that had already appeared in the previous day’s New York Times. A friend who works in intelligence once joked that Stratfor is just The Economist a week later and several hundred times more expensive. As of 2001, a Stratfor subscription could cost up to $40,000 per year.

Fisher also chide Wikileaks for buying into Stratfor’s marketing hype:

It’s true that Stratfor employs on-the-ground researchers. They are not spies. On today’s Wikileaks release, one Middle East-based NGO worker noted on Twitter that when she met Stratfor’s man in Cairo, he spoke no Arabic, had never been to Egypt before, and had to ask her for directions to Tahrir Square. Stratfor also sometimes pays “sources” for information. Wikileaks calls this “secret cash bribes,” hints that this might violate the Foreign Corrupt Practices Act, and demands “political oversight.”

For comparison’s sake, The Atlantic often sends our agents into such dangerous locales as Iran or Syria. We call these men and women “reporters.” Much like Statfor’s agents, they collect intelligence, some of it secret, and then relay it back to us so that we may pass it on to our clients, whom we call “subscribers.” Also like Stratfor, The Atlantic sometimes issues “secret cash bribes” to on-the-ground sources, whom we call “freelance writers.” We also prefer to keep their cash bribes (“writer’s fees”) secret, and sometimes these sources are even anonymous.

The Atlantic: Stratfor Is a Joke and So Is Wikileaks for Taking It Seriously

I suppose much of that depends on whether these payments were made to, as Fisher suggests, freelance researchers/writers, or to, as Wikileaks implies, to government officials and employees. The Stratfor employee mentioned by that NGO worker may not be the only type of “informant” on the company’s pay role.

(via Alex Burns)

See also:

Inside the World of Wannabe Cyberspooks for Hire

Anonymous Publishes E-Mail Saying Stratfor CEO to Resign Over Wikileaks E-Mail Dump

Anonymous Reveals Private Intelligence Firm Stratfor Infiltrated Occupy Austin

From http://feedproxy.google.com/~r/Technoccult/~3/g7xAWfrRzU4/

The Neuroscience of Video Games, a Review of the Literature

  • Posted on November 23, 2011 at 8:49 pm

gamer 01 The Neuroscience of Video Games, a Review of the Literature

John Walker takes a look at the journal Nature‘s recent Brains On Video Games collection, which includes both possible negative and possible positive outcomes of video game play.

The bad news: much of the positive cognitive gains from video gaming are non-transferable, and gaming may increase both aggression and the symptoms of ADHD. The good news: it doesn’t sound like that should be a problem for people without existing aggressive tendencies or ADHD.

My take-away: if you like playing games, keep playing them. If you don’t, there’s probably not much benefit in starting.

Rock, Paper Shotgun: Nature’s Neuroscientific Review Of Games

See also:

Video Games Boost Brain Power, Multitasking Skills

Video Games and Spatial Cognition (PDF)

Video Gamers Are Better Lucid Dreamers?

From http://feedproxy.google.com/~r/Technoccult/~3/LULnM8aom7Q/

The Neuroscience of Video Games, a Review of the Literature

  • Posted on November 23, 2011 at 8:49 pm

gamer 01 The Neuroscience of Video Games, a Review of the Literature

John Walker takes a look at the journal Nature‘s recent Brains On Video Games collection, which includes both possible negative and possible positive outcomes of video game play.

The bad news: much of the positive cognitive gains from video gaming are non-transferable, and gaming may increase both aggression and the symptoms of ADHD. The good news: it doesn’t sound like that should be a problem for people without existing aggressive tendencies or ADHD.

My take-away: if you like playing games, keep playing them. If you don’t, there’s probably not much benefit in starting.

Rock, Paper Shotgun: Nature’s Neuroscientific Review Of Games

See also:

Video Games Boost Brain Power, Multitasking Skills

Video Games and Spatial Cognition (PDF)

Video Gamers Are Better Lucid Dreamers?

From http://feedproxy.google.com/~r/Technoccult/~3/LULnM8aom7Q/

Reverse Placebo: People Wrongly Diagnosed with Alzheimer’s Go Senile

  • Posted on August 30, 2011 at 9:50 am

Psychologists in the Netherlands have documented the case of a 58-year-old woman who was misdiagnosed with Alzheimer’s Disease. Her condition deteriorated to the point where she became permanently confused, and at one point suicidal — before another doctor realized the diagnosis was incorrect.

What happens to people who are wrongly diagnosed with having cognitive difficulties? It turns out that even if your brain is perfectly healthy, you’ll start having more problems with concentration.

io9: What happens when you’re wrongly diagnosed with Alzheimer’s Disease

(Thanks Bill!)

See also: The placebo effect is real apparently even when you know it’s a placebo

From http://feedproxy.google.com/~r/Technoccult/~3/sfvKHNEt7S0/

What’s Next for Cognitive Training Games?

  • Posted on June 25, 2011 at 6:37 pm

brain Whats Next for Cognitive Training Games?

Most of the cognitive training games of 2011 resemble the simple games you can play online for free or apps designed for smartphones. However, in ten years, we can expect many of the big developers, following Nintendo’s lead, to introduce critical gaming elements. Envision games featuring improved graphics, compelling gameplay, and engaging storylines that compel players to train their brains often and in a variety of ways. Imagine a role-playing game (RPG) in which your character’s level and progress are determined in part by your performance on a variety of cognitive training tasks, and the selection of tasks are dependent on the class chosen by the player, and thus tailored made for each individual user. Much in the same way that RPG style games will foster unique training experiences, cognitive training games in general will become tailored to individual interests, focusing on training specific cognitive mechanisms, rather than providing a general training regimen that the user may not be looking for. [...]

Non-Conscious Defenses- Starting all the way back in the 1950’s, firms have sought to understand human psychology in order to capitalize on our biases and tendencies through influencing us on the sub-conscious level. In the past couple decades however, research into non-conscious processing and subliminal priming have begun to unravel the fascinating ways that people develop preferences for products and how they estimate value. Companies have been following this research closely and already implement their findings into many forms of media: magazines, movies and even presidential election commercials (5). Expect that training games will begin to offer cognitive defenses against advertising seeking to influence us on the sub conscious level.

The Future of Brain Workouts

See also: N-Back Training Exercise Still Holding Up in Tests

From http://feedproxy.google.com/~r/Technoccult/~3/700QNMBpqI8/

5 Reasons Why Having a High IQ Ain’t All It’s Cracked-Up to Be

  • Posted on June 10, 2011 at 9:30 am

OddJohn 5 Reasons Why Having a High IQ Aint All Its Cracked Up to Be

Yes, it’s from Cracked, but it’s interesting:

#5.You’re Probably a Night Owl — And That’s a Bad Thing
#4.You’re Less Likely to Pass On Your Genes
#3. You’re More Likely to Lie
#2. You’re More Likely to Believe Bullshit
#1. You’re More Likely to Be Self-Destructive

Cracked: 5 Unexpected Downsides of High Intelligence

See also:

Why Smart People Do More Drugs

Smart kids more likely to be heavy drinkers

(via Dr. Benway)

From http://technoccult.net/archives/2011/06/10/5-reasons-having-a-high-iq-aint-all-its-cracked-up-to-be/

Coffee: The Original Smart Drug and Aphrodisiac

  • Posted on April 18, 2011 at 10:50 am

Coffee: Grounds for Debate, a title in the Philosophy for Everyone series, argues that coffee is a performance-enhancing drug for thinkers. “The appropriate analogy is that coffee and philosophy go together like foreplay and sex,” insist editors Scott F Parker and Michael W Austin. “You can have one without the other, but the latter is better with the former and the former often leads to the latter.” Philosopher Basam Romaya says: “With the use of coffee, critical thinking abilities are sharpened, attention to detail enhanced.” This is a venerable claim: in the 16th century, Sheik Abd-al-Kadir, an Arab scholar, said: “No one can understand the truth until he drinks of coffee’s frothy goodness.” [...]

So what about impotence? That does seem to have been overstated. The Women’s Petition Against Coffee prompted a broadside from men who argued that it “makes the erection more Vigorous, the Ejaculation more full, adds spiritualescency to the Sperme”. Initially I wasn’t sure what “spiritualescency” means, either, until I read in this book that caffeine increases sperm motility. That said, some say coffee may harm the sperm while speeding it on its way, which makes a kind of sense.

The Guardian: Can coffee wreck your marriage?

(via James Governor)

From http://technoccult.net/archives/2011/04/18/coffee-the-original-smart-drug-and-aphrodisiac/

7 Ways to Amplify Your Intelligence

  • Posted on March 8, 2011 at 9:53 am

human brain activity 7 Ways to Amplify Your Intelligence

Plot of one second of human brain (EEG) activity, from the Sounds Of Complexity by Enzo Varriale via Flickr

Andrea Kuszewski writes about five ways to amplify your intelligence for Scientific American. I’ve added two additional techniques.

Kuszewski’s list:

1. Seek Novelty – “People who rate high on Openness are constantly seeking new information, new activities to engage in, new things to learn—new experiences in general.”

2. Challenge Yourself – “Individual brain training games don’t make you smarter—they make you more proficient at the brain training games,” Kuszewski writes. “Once you master one of those cognitive activities in the brain-training game, you need to move on to the next challenging activity. Figure out how to play Sudoku? Great! Now move along to the next type of challenging game.” (Previous Technoccult coverage)

3. Think Creatively – “Contrary to popular belief, creative thinking does not equal ‘thinking with the right side of your brain.’ It involves recruitment from both halves of your brain, not just the right.” (Previous coverage)

4. Do Things the Hard Way “There are times when using technology is warranted and necessary. But there are times when it’s better to say no to shortcuts and use your brain, as long as you can afford the luxury of time and energy.”

5. Network “By networking with other people—either through social media such as Facebook or Twitter, or in face-to-face interactions—you are exposing yourself to the kinds of situations that are going to make objectives 1-4 much easier to achieve.” (Previous coverage)

Scientific American: You can increase your intelligence: 5 ways to maximize your cognitive potential

Here are my bonus tips:

Get more sleep.

Meditate.

From http://feedproxy.google.com/~r/Technoccult/~3/Sq9ab-5Kn8I/

Humanity’s Next Evolution May Be Mental, Not Biological

  • Posted on February 28, 2011 at 12:24 pm

Mark Changizi, author of the upcoming book Harnessed: How Language and Music Mimicked Nature and Transformed Man, writes:

Where are we humans going, as a species? If science fiction is any guide, we will genetically evolve like in X-Men, become genetically engineered as in Gattaca, or become cybernetically enhanced like General Grievous in Star Wars. [...]

Simply put, none of these scenarios are plausible for the immediate future. [...]

We have already been transformed via harnessing beyond what we once were. We’re already Human 2.0, not the Human 1.0, or Homo sapiens, that natural selection made us. We Human 2.0’s have, among many powers, three that are central to who we take ourselves to be today: writing, speech, and music (the latter perhaps being the pinnacle of the arts). Yet these three capabilities, despite having all the hallmarks of design, were not a result of natural selection, nor were they the result of genetic engineering or cybernetic enhancement to our brains. Instead, and as I argue in both The Vision Revolution and my forthcoming Harnessed, these are powers we acquired by virtue of harnessing, or neuronal recycling.

In this transition from Human 1.0 to 2.0, we didn’t directly do the harnessing. Rather, it was an emergent, evolutionary property of our behavior, our nascent culture, that bent and shaped writing to be right for our visual system, speech just so for our auditory system, and music a match for our auditory and evocative mechanisms. [...]

The road to Human 3.0 and beyond will, I believe, be largely due to ever more instances of this kind of harnessing. And although we cannot easily anticipate the new powers we will thereby gain, we should not underestimate the potential magnitude of the possible changes. After all, the change from Human 1.0 to 2.0 is nothing short of universe-rattling: It transformed a clever ape into a world-ruling technological philosopher.

Seed: THE NEXT GIANT LEAP IN HUMAN EVOLUTION MAY NOT COME FROM NEW FIELDS LIKE GENETIC ENGINEERING OR ARTIFICIAL INTELLIGENCE, BUT RATHER FROM APPRECIATING OUR ANCIENT BRAINS

(via Justin Pickard)

From http://feedproxy.google.com/~r/Technoccult/~3/N93vAocMgSc/

As Humans Evolve, Our Brains Are Actually Getting Smaller

  • Posted on January 4, 2011 at 7:51 pm

leader As Humans Evolve, Our Brains Are Actually Getting Smaller

Today’s human brain is about 10 percent smaller than the Cro-Magnon brain from more than 20,000 years ago.

When it comes to brain size, bigger doesn’t always mean better. As humans continue to evolve, scientists say our brains are actually getting smaller. [...]

Cro-Magnon man, who lived in Europe 20,000 to 30,000 years ago, had the biggest brains of any human species. In comparison, today’s human brain is about 10 percent smaller. It’s a chunk of brain matter “roughly equivalent to a tennis ball in size,” McAuliffe says.

The experts aren’t sure about the implications of this evolutionary trend. Some think it might be a dumbing-down process. One cognitive scientist, David Geary, argues that as human society grows increasingly complex, individuals don’t need to be as intelligent in order to survive and reproduce.

But not all researchers are so pessimistic. Brian Hare, an anthropologist at the Duke University Institute for Brain Sciences, thinks the decrease in brain size is actually an evolutionary advantage.

NPR: Our Brains Are Shrinking. Are We Getting Dumber?

From http://feedproxy.google.com/~r/Technoccult/~3/xG-2-VTONmM/

Are Stoners Really Dumb, or Do They Just Think They Are?

  • Posted on November 29, 2010 at 5:50 pm

Stoner cropped

Earleywine and his colleagues studied 57 users, 30 male and 27 female. Half were given material to read suggesting that marijuana damages the brain; the other half read a research summary suggesting that the drug had no long-term negative cognitive effects. Then, all participants were asked to take cognitive tests after abstaining from marijuana for at least one day. (More on Time.com: See photos of cannabis conventions)
There was a marked difference in results — interestingly, between men and women. Men who got the negative information about marijuana performed worse than men who didn’t, but the women who were faced with stereotype threat actually scored better on tests of verbal skills and memory than women who weren’t given negative information.

Time: Are Stoners Really Dumb, or Do They Just Think They Are?

From http://feedproxy.google.com/~r/Technoccult/~3/zAEyqwSF-x8/

Group Exhibit Their Own Cognitive Intelligence, Enhanced by Women

  • Posted on October 1, 2010 at 3:04 pm

the groomsmen from my wedding
My groomsmen from my wedding and me. Perhaps not the best example of group intelligence.

When it comes to intelligence, the whole can indeed be greater than the sum of its parts. A new study co-authored by MIT, Carnegie Mellon University, and Union College researchers documents the existence of collective intelligence among groups of people who cooperate well, showing that such intelligence extends beyond the cognitive abilities of the groups’ individual members, and that the tendency to cooperate effectively is linked to the number of women in a group.

PhysOrg: Study finds small groups demonstrate distinctive ‘collective intelligence’ when facing difficult tasks

From http://feedproxy.google.com/~r/Technoccult/~3/h34aMcMTotg/

Are Distractible People More Creative?

  • Posted on September 16, 2010 at 5:34 pm

Focus of Attention

Consider a recent study by neuroscientists at Harvard and the University of Toronto that documents the benefits of all these extra thoughts. (It was replicated here.) The researchers began by giving a sensory test to a hundred undergraduates at Harvard. The tests were designed to measure their level of latent inhibition, which is the capacity to ignore stimuli that seem irrelevant. Are you able to not think about the air-conditioner humming in the background? What about the roar of the airplane overhead? When you’re at a cocktail party, can you tune out the conversations of other people? If so, you’re practicing latent inhibition. While this skill is typically seen as an essential component of attention – it keeps us from getting distracted by extraneous perceptions – it turns out that people with low latent inhibition have a much richer mixture of thoughts in working memory. This shouldn’t be too surprising: Because they struggle to filter the world, they end up letting everything in. As a result, their consciousness is flooded with seemingly unrelated thoughts. Here’s where the data gets interesting: Those students who were classified as “eminent creative achievers” – the rankings were based on their performance on various tests, as well as their real world accomplishments – were seven times more likely to “suffer” from low latent inhibition. This makes some sense: The association between creativity and open-mindedness has long been recognized, and what’s more open-minded than distractability? People with low latent inhibition are literally unable to close their mind, to keep the spotlight of attention from drifting off to the far corners of the stage. The end result is that they can’t help but consider the unexpected.

Wired: Are Distractible People More Creative?

See also: The Attention-Allocation Deficit

Photo by Hartwig HKD

From http://feedproxy.google.com/~r/Technoccult/~3/2PCCDWn1jYo/

UK Considers Regulating Intelligence Enhancing Drugs

  • Posted on August 4, 2010 at 3:32 pm

Provigil

The government’s official experts on illegal drugs have been asked to look at whether intelligence-enhancing drugs, such as those used by students to boost performance in exams, should be banned.

Medical experts believe that a range of psychoactive drugs that includes those used to tackle the symptoms of Alzheimer’s and attention-deficit disorder in children, could fuel an already over-competitive society when used by the healthy.

Amid fears that the increase in online pharmacies means that such drugs are much more readily available, the Home Office has asked the Advisory Council on the Misuse of Drugs to see how this “rapidly evolving field” should be regulated. Just before she stepped down from office, the previous home secretary, Jacqui Smith, asked the advisory council to assess the harm – including that of possible psychological dependence or addiction – caused by this group of drugs when used by healthy adults.

Guardian: Government watchdog considers ban on IQ booster drugs

Photo by nym (CC)

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From http://technoccult.net/archives/2010/08/04/smart-drug-ban/